High Fluoride Concentration and Amelioration Effect in Haematological Parameter after Supplementary Diet Aloe Vera in Albino Rat (rattus Norvegicus)

Haematological parameters in Albino rats were altered after exposure to sodium fluoride. Static bioassay experiments were conducted to find out Lc50 with the administration of oral dose of 10.00ppm of Naf per kg of body weight to adult healthy albino rats. The experimental doses were set up for the three groups of animals each having 4 animals for 30, 60 & 90 days time interval. Blood samples were analyzed for haematological parameters after exposure of dose for particular duration. Alteration in different parameters viz. RBC count,WBC count, Haemoglobin, Acidphosphatase, Alkaline phosphatase.Protein,Cholesterol, glycogen, SGOT, SGPT, urea, creatinine were estimated in serum of treated animals and results were compared with control set of experiment.In present investigation, Aloe vera is significantly used to fluoride exposed rats to reduce the toxic risk of fluoride, exhibiting restoration.